Klinefelter's Syndrome

From Transgender Wiki
Jump to: navigation, search

Commonly misspelled Kleinfelter's Syndrome

Klinefelter's Syndrome, 47, XXY and XXY syndrome refer to a condition in which a male has an extra X chromosome. Normal male human DNA consists of 46 chromosomes (44 autosomal and 2 sex-linked chromosomes); in people with Klinefelter's Syndrome there is an extra X chromosome, bringing the count to 47. The most common symptom is infertility, though other symptoms such as sparse facial and body hair, small testes and gynecomastia may also manifest.

The syndrome was named after the phenotype was first described by Dr. Harry Klinefelter and his coworkers in 1942. Later studies have placed the incidence of Klinefelter's Syndrome in the general population at 1 in 500 to 1 in 1000 births, making it one of the most common genetic anomalies. [1]

Personal Experience

We hope to soon have personal experiences of those with Klinefelter's Syndrome posted here.


  1. "Understanding Klinefelter Syndrome" National Institutes of Health. Eunice Kennedy Shriver National Institute of Child Health and Human Development, Aug. 1993. Web. 24 Apr. 2011.
Personal tools